You Have to be From Philly to Get This Joke

Gizmodo is featuring these fun fire screens where you can have the city of Rome, or City of London silhouetting your fire.  First commenter on this says:

As a Philly native, I’m holding out for the Ogontz Ave. rowhomes, circa 1985.

Not very tasteful, but then again, neither is the city. For those of you not familiar, see here. BTW, it was Osage Ave, not Ogontz.

WTF in Wisconsin

Wisconsin’s tourism lobby group is changing their name. Why? Because when it was named the Wisconsin Tourism Federation 30 years ago, the acronym WTF didn’t have any meaning. Nowadays…well, you read the interwebz.

As I told JR Absher, this is really too bad. If they were really innovative, they could have embraced the acronym when appropriate. I could see some great ad campaigns to attract younger visitors playing off the name. Or, since they are a lobby coalition, if a piece of particularly egregious legislation was introduced, it would be a fun political ad that would get the attention of legislative staffers if used properly.

A New Meaning to “Rubbing One Out”

Looks like they are developing a topical medication for erectile dysfunction.  Meaning you rub it you know where. This presents us with some hilarity:

A topical cream for erectile dysfunction shows promise in animal testing and could become an alternative for men who can’t tolerate the pill form of the drugs, U.S. researchers report.

Typical animals you’ll test on in a trial are rats, dogs, and sometimes simians. I’m pretty sure that’s going to be a job they give to the intern. I wouldn’t imagine that kind of job is what you thought you were signing up for when you got your degree in biology or animal sciences. But what about when it goes to human trials?

Clinical trials on humans typically recruit healthy young people, using double blind studies with some study groups getting the drug, and others getting placebo. In this case, you won’t be able to use healthy young males, because your placebo is liable to be 100% effective. So trials will definitely have to seek out people who have erectile difficulties, which is typically not your healthy young males.

But it’s a good development if it works. Viagra was actually meant to treat high blood pressure and angina, but it wasn’t terribly good at that. Rumor has it that people in the trials asked if they could keep getting more of the drug, and when researched discovered why, they realized that its side effect was worth more than it was for the initial disease. But Viagra still has effects on the cardiovascular system, so it’s not well tolerated by everyone.

A Monday Chuckle

I’m busy doing a last round of cleaning and laundry today before we have guests over to eat.  To amuse myself, I am attempting to start a small Twitter meme based on jokes Sebastian and I were making this weekend.  So, if you’re on Twitter, feel free to contribute to #GunNutPickupLines.  Amuse me, amuse yourselves, and forget it’s Monday.